Mississippi Car Transportation Routes and Highways
| Interstate Highways | |||
|---|---|---|---|
| I-10: Runs east-west along the Gulf Coast, connecting major cities such as Gulfport and Biloxi, and extends from the Louisiana border to the Alabama border. | |||
| I-20: Traverses the central part of the state, running east-west through cities like Vicksburg, Jackson, and Meridian, connecting Louisiana to Alabama. | |||
| I-22: Located in the northern part of Mississippi, it connects Memphis, Tennessee, to Birmingham, Alabama, passing through Tupelo. | |||
| I-55: Runs north-south through the state, connecting Louisiana to Tennessee, and passes through cities like Jackson and McComb. | |||
| I-59: Enters Mississippi near Picayune, runs northeast through Hattiesburg and Meridian, and continues into Alabama. | |||
| I-69: Currently under development, with segments open in the northwestern part of the state, aiming to connect to the broader I-69 corridor. | |||
| I-110: A short spur connecting I-10 to downtown Biloxi. | |||
| U.S. Routes: | |||
|---|---|---|---|
| US 11: Runs parallel to I-59, connecting Louisiana to Alabama through cities like Hattiesburg and Meridian. | |||
| US 45: Extends north-south from the Gulf Coast at Mobile, Alabama, through Meridian and Tupelo, continuing into Tennessee. | |||
| US 49: Connects Gulfport on the Gulf Coast to Jackson and continues northward, serving as a major route for both passenger and freight traffic. | |||
| US 61: Known as the "Blues Highway," it runs along the western edge of the state, paralleling the Mississippi River, and connects cities like Natchez and Vicksburg. | |||
| US 82: Crosses the state east-west, connecting Greenville, Greenwood, and Columbus, and continues into Alabama and Arkansas. | |||
| US 84: Runs east-west through southern Mississippi, connecting Natchez, Brookhaven, and Laurel, extending from the Louisiana border to the Alabama border. | |||
| US 98: Traverses the southern part of the state, connecting Natchez, Hattiesburg, and Lucedale, and continues into Alabama. | |||
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