| Interstate Highways: | |||
|---|---|---|---|
| I-40: Runs east-west across North Carolina, connecting Wilmington through Greensboro and extending to the Tennessee border. An important highway for reliable North Carolina auto transport. | |||
| I-85: Traverses north-south through central North Carolina, connecting Charlotte to Durham and the Virginia border. | |||
| I-95: Runs north-south along the eastern part of the state, connecting Jacksonville, Fayetteville, and extending from the South Carolina to Virginia borders. | |||
| I-26: Enters North Carolina from South Carolina, passing through Asheville and extending toward Tennessee. | |||
| I-77: Connects Charlotte to Columbia, South Carolina, running north-south through the western part of the state. | |||
| I-74: Runs through the southeastern part of North Carolina, connecting Rockingham to Wilmington. | |||
| I-240: A loop around Asheville, providing alternate routes around the city. It is a key route for open auto transport in North Carolina. | |||
| I-440: A beltway around Raleigh. | |||
| I-540: An outer loop around Raleigh, extending north and south of the city. | |||
| I-140: A bypass around Wilmington. | |||
| U.S. Highways: | |||
|---|---|---|---|
| US 1: Runs north-south through eastern North Carolina, connecting the South Carolina border to Virginia. | |||
| US 17: Traverses the coastal region from South Carolina to Virginia. | |||
| US 64: A major route for open transport in areas in North Carolina. Crosses the state from the Tennessee border through Raleigh to the Outer Banks. | |||
| US 70: Runs east-west across the state, connecting Asheville to Morehead City. | |||
| US 74: Connects Charlotte to Wilmington, crossing the state east to west. | |||
| US 276: Provides access through the mountainous regions near Brevard. | |||
| US 25: Runs north-south through western North Carolina, connecting South Carolina to Tennessee. | |||
| US 221: Serves the western mountain regions of the state. | |||
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